Premature multiple Bowen's disease in poikiloderma congenitale with warty hyperkeratoses.

Abstract	A constant gradual malignant degeneration of verrucous hyperkeratoses was observed in a now 16-year-old poikiloderma congenitale patient although topical immunotherapy of the warty lesions was partially successful and led to an improvement of T-cell functions.
Authors	E Haneke, E Gutschmidt
Journal	Dermatologica (Dermatologica) Vol. 158 Issue 5 Pg. 384-8 ( 1979) ISSN: 0011-9075 [Print] Switzerland
PMID	437227 (Publication Type: Case Reports, Journal Article)
Chemical References	Dinitrochlorobenzene Nitrobenzenes
Topics	Administration, Topical Adolescent Bowen's Disease (etiology, pathology, therapy) Carcinoma, Squamous Cell (etiology) Dinitrochlorobenzene (therapeutic use) Female Humans Immunologic Deficiency Syndromes (complications, immunology, therapy) Immunotherapy Keratosis (complications, pathology, therapy) Nitrobenzenes (therapeutic use) Retinal Degeneration (complications) Rothmund-Thomson Syndrome (complications, immunology) Skin (pathology) Skin Diseases (complications) Warts (complications, pathology, therapy)

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