Younger age of presentation and extraosseous tumour in IgD myelomatosis.

Abstract

A study of 14 personal patients and 16 others in the literature shows that (1) IgD myelomatosis often presents at a significantly younger age than other forms of myelomatosis, and (2) during life extraosseous tumour can be detected in about two-thirds of these patients.The IgD form represents 1.5% of myelomatosis and shows an increased incidence of osteolytic lesions, hypercalcaemia, and renal failure, together with heavy Bence Jones proteinuria (90% type L).Like only Bence Jones myelomatosis, the IgD form seems to behave clinically in a more vicious manner.

• Authors: J R Hobbs, A A Corbett
• Journal: British medical journal (Br Med J) Vol. 1 Issue 5641 Pg. 412-4 (Feb 15 1969) ISSN: 0007-1447 [Print] England
• PMID: 4179168 (Publication Type: Journal Article)

Chemical References

• gamma-Globulins
• Bence Jones Protein

Topics

• Adult
• Age Factors
• Aged
• Bence Jones Protein (urine)
• Blood Protein Disorders (complications)
• Bone Resorption (etiology)
• Female
• Humans
• Hypercalcemia (etiology)
• Kidney Failure, Chronic (etiology)
• Male
• Middle Aged
• Multiple Myeloma (complications)
• Neoplasm Metastasis
• Proteinuria (complications)
• gamma-Globulins (analysis)