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Comparison of animal infectivity and excystation as measures of Giardia muris cyst inactivation by chlorine.

Abstract
In this study, in vitro excystation and mouse infectivity were compared as methods for quantitatively determining the viability of Giardia muris cysts before and after exposure to free residual chlorine. The mouse infectivity results show that very few cysts (1 to 15) constitute an infectious dose. The results of the inactivation studies indicate that in vitro excystation is an adequate indication of G. muris cyst infectivity for the host and can be used to determine the effects of disinfectants on cyst viability.
AuthorsJ C Hoff, E W Rice, F W Schaefer 3rd
JournalApplied and environmental microbiology (Appl Environ Microbiol) Vol. 50 Issue 4 Pg. 1115-7 (Oct 1985) ISSN: 0099-2240 [Print] United States
PMID4083876 (Publication Type: Journal Article)
Chemical References
  • Chlorine
Topics
  • Animals
  • Chlorine (pharmacology)
  • Giardia (drug effects, growth & development, pathogenicity)
  • Giardiasis (parasitology)
  • Mice

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