Nocturnal plasma prolactin rise in patients with complex partial seizures.

Abstract

We measured plasma prolactin and cortisol concentrations in 12 epileptic men with complex partial seizures during all-night polygraphic recording, with continuous video monitoring and sequential blood sampling at 30-minute intervals. There was a significant but moderate elevation of all-night mean plasma prolactin concentration (p less than 0.001), but not of cortisol, in epileptics when compared with normal subjects studied in a similar fashion. The data obtained in this environmentally controlled study of males with complex partial seizure disorder indicate a disruption of prolactin regulatory mechanisms resulting in a modest elevation of plasma concentrations independent of ictal electrographic discharges.

• Authors: M Molaie, A Culebras, M Miller
• Journal: Annals of neurology (Ann Neurol) Vol. 18 Issue 6 Pg. 719-22 (Dec 1985) ISSN: 0364-5134 [Print] United States
• PMID: 4083853 (Publication Type: Journal Article)

Chemical References

• Prolactin

Topics

• Adult
• Aged
• Electroencephalography
• Epilepsy, Temporal Lobe (blood, complications)
• Humans
• Male
• Middle Aged
• Prolactin (blood)
• Sexual Dysfunction, Physiological (etiology)