Treatment of oligozoospermia with tamoxifen (open and controlled studies).

Abstract

Open and double-blind therapeutic studies were carried out on the effects of tamoxifen in oligozoospermia. The examinations involved 74 patients. The first group (n = 20) received tamoxifen 20 mg/day; the second group (n = 54) got tamoxifen or placebo for 3 months. In the open study, tamoxifen treatment led to significant increases in the spermatozoa concentration and the total sperm count, but this could not be confirmed with the double-blind set-up.

• Authors: L Török
• Journal: Andrologia (Andrologia) 1985 Sep-Oct Vol. 17 Issue 5 Pg. 497-501 ISSN: 0303-4569 [Print] Germany
• PMID: 4061890 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)

Chemical References

• Tamoxifen

Topics

• Adult
• Double-Blind Method
• Female
• Humans
• Male
• Oligospermia (drug therapy)
• Pregnancy
• Sperm Count (drug effects)
• Sperm Motility (drug effects)
• Tamoxifen (therapeutic use)