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Efficacy of fenbendazole and cambendazole against Muellerius capillaris in dairy goats.

Abstract
Two anthelmintics, fenbendazole and cambendazole, were used in an attempt to eliminate Muellerius capillaris infections in a group of 44 goats. During the course of this study (508 days), M capillaris larvae were found in at least one fecal specimen from each of 22 of the 44 goats. All 44 goats were dewormed with fenbendazole (30 mg/kg of body weight) at the onset of this study (day 18). Two additional dewormings with fenbendazole at 4- to 8-week intervals were restricted to the goats that continued to shed M capillaris larvae. On the basis of routine fecal examinations, fenbendazole eliminated M capillaris larvae from the feces of 8 (36%) of these 22 goats. On day 253, cambendazole (60 mg/kg) was given orally to 17 of these 22 goats (2 of the 22 had died and 3 were not available for treatment); 13 of these goats were still shedding M capillaris larvae. Cambendazole eliminated M capillaris larvae from the feces of 10 (77%) of these 13 goats chronically infected with M capillaris.
AuthorsE L Bliss, E C Greiner
JournalAmerican journal of veterinary research (Am J Vet Res) Vol. 46 Issue 9 Pg. 1923-5 (Sep 1985) ISSN: 0002-9645 [Print] UNITED STATES
PMID4051297 (Publication Type: Comparative Study, Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)
Chemical References
  • Benzimidazoles
  • Cambendazole
  • Fenbendazole
Topics
  • Animals
  • Benzimidazoles (therapeutic use)
  • Cambendazole (therapeutic use)
  • Feces (parasitology)
  • Female
  • Fenbendazole (therapeutic use)
  • Goats
  • Larva (isolation & purification)
  • Lung Diseases, Parasitic (drug therapy, parasitology, veterinary)
  • Nematoda (isolation & purification)
  • Nematode Infections (drug therapy, parasitology, veterinary)

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