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Usefulness of heparin in initial management of patients with recent transient ischemic attacks.

Abstract
We evaluated the efficacy of short-term intravenous heparin therapy in 74 patients with recent transient ischemic attacks (TIAs). The patients were treated after hospitalization until operation or long-term medical treatment was instituted. Heparin was given in a continuous infusion to maintain an activated partial thromboplastin time of 1 1/2 to 2 1/2 times control values. During the treatment period, 12 patients (16.2%) had recurrent TIAs and five (6.8%) had cerebral infarction. Bleeding complications occurred in nine patients (12.2%). In this limited series, heparin did not prevent recurrent TIAs or cerebral infarction among high-risk patients with recent TIAs.
AuthorsS F Putman, H P Adams Jr
JournalArchives of neurology (Arch Neurol) Vol. 42 Issue 10 Pg. 960-2 (Oct 1985) ISSN: 0003-9942 [Print] United States
PMID4038103 (Publication Type: Journal Article)
Chemical References
  • Heparin
Topics
  • Adult
  • Aged
  • Cerebral Infarction (etiology, prevention & control)
  • Female
  • Heparin (adverse effects, therapeutic use)
  • Humans
  • Ischemic Attack, Transient (complications, drug therapy)
  • Male
  • Middle Aged

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