[LDL-apheresis in the treatment of familial hypercholesterolemia].

Abstract

Several non-pharmacological treatments have been tested for homozygous familial hypercholesterolemia and, among these, plasma-exchange has been the most safe and effective. A recent development of this procedure is LDL-apheresis, that is the selective removal of atherogenic LDL and the return to the patient of his own LDL-depleted plasma. The method is based on the flowing of hypercholesterolemic plasma on sepharose columns with bound anti-LDL antibodies.

• Authors: N Scarpato, A Postiglione
• Journal: La Ricerca in clinica e in laboratorio (Ric Clin Lab) Vol. 15 Suppl 1 Pg. 499-504 ( 1985) ISSN: 0390-5748 [Print] Italy
• Vernacular Title: LDL-aferesi nel trattamento dell'ipercolesterolemia familiare.
• PMID: 4035229 (Publication Type: English Abstract, Journal Article)

Chemical References

• Lipoproteins, LDL

Topics

• Humans
• Hyperlipoproteinemia Type II (therapy)
• Lipoproteins, LDL (blood)
• Methods
• Plasmapheresis