[Clinical efficacy of cefpimizole in inflammatory diseases in the field of gynecology].

Abstract

Clinical study to evaluate the usefulness of cefpimizole (AC-1370) was made in the 6 patients with female genital organ infections. Two grams or 4 g of AC-1370 was administered a day by intravenous drip infusion ranging from 5 to 18 days. Responses were excellent in 2 cases, good in 3 cases and poor in 1 case, parametritis after hysterectomy. The efficacy rate was 83%. Neither general side effect nor abnormal laboratory finding was observed. AC-1370 showed a satisfactory clinical efficacy in treatment of the infections in the field of gynecology, and it has been concluded that AC-1370 will be an useful antibiotic for these infections.

• Authors: K Okamura, M Nakakuki, H Nagai, S Koga, J Akama
• Journal: The Japanese journal of antibiotics (Jpn J Antibiot) Vol. 38 Issue 4 Pg. 911-4 (Apr 1985) ISSN: 0368-2781 [Print] Japan
• PMID: 4032727 (Publication Type: English Abstract, Journal Article)

Chemical References

• Cephalosporins
• cefpimizole

Topics

• Adult
• Bacterial Infections (drug therapy)
• Cephalosporins (administration & dosage, adverse effects, therapeutic use)
• Drug Evaluation
• Female
• Genital Diseases, Female (drug therapy)
• Humans
• Infusions, Parenteral
• Middle Aged