Abstract |
The experimental data suggest that permeability changes at the plasma membrane level are the most likely cause of the enhancement of tumor cell killing by hyperthermia in the presence of 1 mM La3+. The interaction of La3+ with the Na+, K+ ATPase and Ca2+-pump ATPase may be the probable cause of dramatic electrolyte changes which enhance the hyperthermia effects on tumor cells.
|
Authors | L J Anghileri, M C Crône, J Robert |
Journal | Neoplasma
(Neoplasma)
Vol. 32
Issue 3
Pg. 369-73
( 1985)
ISSN: 0028-2685 [Print] Slovakia |
PMID | 4022197
(Publication Type: Journal Article)
|
Chemical References |
- Electrolytes
- Lanthanum
- Rubidium
- Potassium
- Calcium
|
Topics |
- Animals
- Calcium
(metabolism)
- Cell Membrane Permeability
- Cell Survival
- Electrolytes
(metabolism)
- Hot Temperature
- Lanthanum
(pharmacology)
- Membrane Fluidity
- Mice
- Neoplasms, Experimental
(metabolism)
- Potassium
(metabolism)
- Rubidium
(metabolism)
|