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Oral treatment of peritonitis complicating continuous ambulatory peritoneal dialysis.

Abstract
The efficacy of oral treatment with cephradine in peritonitis associated with continuous ambulatory peritoneal dialysis (CAPD) was compared with that of intraperitoneal cefuroxime over one year. There were 29 episodes of peritonitis in each group and a primary cure was achieved in 66% of the patients treated with cephradine compared with 55% of the patients treated with cefuroxime, suggesting that oral cephradine is as effective as a treatment with intraperitoneal cefuroxime. Nineteen of the 29 episodes in each treatment group were considered suitable for out-patient management and there was no difference in the success rate of either antibiotic regimen. The results suggest that out-patient treatment with oral cephradine is an efficient way of treating CAPD peritonitis.
AuthorsM Searle, G V Raman
JournalClinical nephrology (Clin Nephrol) Vol. 23 Issue 5 Pg. 241-4 (May 1985) ISSN: 0301-0430 [Print] Germany
PMID4006333 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Cephalosporins
  • Cephradine
  • Cefuroxime
Topics
  • Administration, Oral
  • Cefuroxime (administration & dosage, therapeutic use)
  • Cephalosporins (administration & dosage)
  • Cephradine (administration & dosage, therapeutic use)
  • Humans
  • Injections, Intraperitoneal
  • Kidney Failure, Chronic (therapy)
  • Peritoneal Dialysis (adverse effects)
  • Peritoneal Dialysis, Continuous Ambulatory (adverse effects)
  • Peritonitis (drug therapy, etiology)

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