Studies on human filariasis in Malaysia: immunoglobulin and complement levels in persons infected with Brugia malayi and Wuchereria bancrofti.

Abstract

Levels of immunoglobulins G, A, M and E as well as complement components C3c and C4 have been determined in populations in various endemic areas in Peninsular Malaysia and also in filariasis patients. High immunoglobulin levels were seen. In the microfilarial-negative group IgG was 2009 mg% while IgE was 3967 I.U./ml. In the filariasis group, Wuchereria bancrofti patients had significantly higher levels of IgG, IgM and IgE, namely, 3314 mg%, 804 mg% and 18400 I.U./ml respectively. The significance of these levels is discussed.

• Authors: M Joon-Wah, M Singh, E H Yap, B C Ho, K L Kang
• Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene (Trans R Soc Trop Med Hyg) Vol. 73 Issue 4 Pg. 395-9 ( 1979) ISSN: 0035-9203 [Print] England
• PMID: 400204 (Publication Type: Journal Article)

Chemical References

• Complement C3
• Complement C4
• Immunoglobulins
• Complement System Proteins

Topics

• Adolescent
• Adult
• Brugia
• Complement C3 (analysis)
• Complement C4 (analysis)
• Complement System Proteins (analysis)
• Female
• Filariasis (immunology)
• Humans
• Immunoglobulins (analysis)
• Male
• Middle Aged
• Wuchereria bancrofti