Abstract |
Increased levels of serum myoglobin (S- myoglobin) were found in 6 investigated patients with hypokaliaemic familial periodic paralysis ( hypoKPP) in their habitual condition. Furthermore, in 3 of the 6, increased levels of serum creatine kinase (S-CK) were found. These findings support the hypothesis that hypoKPP is a permanent myopathy, which is aggravated during attacks. It was found that 1 definite carrier had elevated S- myoglobin and among healthy relatives 6/11 had elevated S- myoglobin and 3/11 elevated S-CK. The use of S- myoglobin and S-CK for carrier detection is discussed.
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Authors | P Wiggers, K Nørregaard-Hansen |
Journal | Acta neurologica Scandinavica
(Acta Neurol Scand)
Vol. 71
Issue 1
Pg. 69-72
(Jan 1985)
ISSN: 0001-6314 [Print] Denmark |
PMID | 3976355
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Isoenzymes
- Myoglobin
- Creatine Kinase
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Topics |
- Adolescent
- Adult
- Aged
- Child
- Creatine Kinase
(blood)
- Female
- Genetic Carrier Screening
- Humans
- Hypokalemia
(enzymology, genetics)
- Isoenzymes
- Male
- Middle Aged
- Myoglobin
(blood)
- Paralyses, Familial Periodic
(enzymology, genetics)
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