Review of the dosing regimens for flurbiprofen. A potent analgesic/anti-inflammatory agent.

Abstract

Flurbiprofen (Ansaid, Upjohn) is an effective analgesic and anti-inflammatory agent. At dosages of 50 mg administered every four to six hours as needed, flurbiprofen's analgesic efficacy has been confirmed in patients with postoperative pain as well as in those with postpartum pain and dysmenorrhea. Data also suggest that flurbiprofen administered 30 minutes before surgery reduced the severity of postoperative pain. In patients with rheumatoid arthritis, osteoarthritis, and numerous other inflammatory disorders, 100 to 200 mg of flurbiprofen in two to four divided doses has led to significant clinical improvement. Studies indicate that 100 mg of flurbiprofen at bedtime effectively decreased night pain and the duration of morning stiffness in patients with rheumatoid arthritis.

• Authors: W R Finch
• Journal: The American journal of medicine (Am J Med) Vol. 80 Issue 3A Pg. 16-8 (Mar 24 1986) ISSN: 0002-9343 [Print] United States
• PMID: 3963023 (Publication Type: Journal Article)

Chemical References

• Anti-Inflammatory Agents
• Propionates
• Flurbiprofen

Topics

• Anti-Inflammatory Agents (administration & dosage)
• Arthritis, Rheumatoid (drug therapy)
• Flurbiprofen (administration & dosage)
• Humans
• Pain (drug therapy)
• Propionates (administration & dosage)