[Preventive medical treatment of recurrent urinary calcium calculi].

Abstract

In 59 out of 80 patients with recurrent renal calcium stones studied between 1977 and 1982 and followed up for 4,5 to 7 years, an index has been used to determine the activity of the disease, before and after treatment with diet, high water intake, thiazide and/or allopurinol. As estimated by variations of the "activity index", the treatment was effective in all groups studied: patients with idiopathic hypercalciuria were prescribed a low purine and oxalate diet and a large water intake associated or not with thiazide; hyperuricosuric patients were treated by the same diet and allopurinol; patients with no metabolic abnormality were submitted to diet and/or thiazide and/or allopurinol. The association of thiazide and allopurinol seems to be a more effective therapy in recurrent stone formers with primary hyperoxaluria than high diuresis and succinimide.

• Authors: B François, P Trolliet, R Cahen, M P Semet
• Journal: Nephrologie (Nephrologie) Vol. 7 Issue 1 Pg. 9-12 ( 1986) ISSN: 0250-4960 [Print] Switzerland
• Vernacular Title: Traitement médical prophylactique des lithiases urinaires calciques récidivantes.
• PMID: 3960261 (Publication Type: English Abstract, Journal Article)

Chemical References

• Succinimides
• Hydrochlorothiazide
• Allopurinol
• Amiloride
• Calcium

Topics

• Adult
• Allopurinol (administration & dosage)
• Amiloride (administration & dosage)
• Calcium (urine)
• Diuresis
• Drug Therapy, Combination
• Female
• Fluid Therapy
• Humans
• Hydrochlorothiazide (administration & dosage)
• Kidney Calculi (prevention & control, urine)
• Male
• Middle Aged
• Recurrence
• Retrospective Studies
• Succinimides (administration & dosage)