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Terfenadine and placebo compared in the treatment of chronic idiopathic urticaria: a randomised double-blind study.

Abstract
Terfenadine, a potent and non-sedative antihistamine, was shown to be effective in chronic idiopathic urticaria in a double-blind crossover placebo controlled trial. An oral twice daily 60 mg dose of terfenadine was given and itch and wheal parameters were assessed daily. Despite the overall effectiveness of terfenadine, a variable response was noted which was similar to that shown in previous studies with other antihistamines.
AuthorsJ Ferguson, K J MacDonald, K J Kenicer
JournalBritish journal of clinical pharmacology (Br J Clin Pharmacol) Vol. 20 Issue 6 Pg. 639-41 (Dec 1985) ISSN: 0306-5251 [Print] England
PMID3937549 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
Chemical References
  • Benzhydryl Compounds
  • Terfenadine
Topics
  • Adult
  • Aged
  • Benzhydryl Compounds (adverse effects, therapeutic use)
  • Chronic Disease
  • Clinical Trials as Topic
  • Double-Blind Method
  • Female
  • Humans
  • Male
  • Middle Aged
  • Random Allocation
  • Terfenadine
  • Urticaria (drug therapy)

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