Acromegaly associated with suprasellar and pulmonary hemangiopericytomas. Case report.

Abstract

The authors report the case of a 35-year-old acromegalic woman who developed amenorrhea and decreased left vision, and who was found to have suprasellar and pulmonary hemangiopericytomas. Total removal of the suprasellar hemangiopericytoma resulted in normalization of the plasma human growth hormone (GH) level and a marked decrease in size of the pulmonary hemangiopericytoma. Immunoperoxidase studies for GH and human hypothalamic growth hormone-releasing factor (GHRF) demonstrated immunoreactive intracellular GH only in the suprasellar hemangiopericytoma, with no immunoreactive intracellular GHRF evident in either the suprasellar or pulmonary hemangiopericytoma.

• Authors: M Yokota, E Tani, Y Maeda, T Morimura, K Kakudo, K Uematsu
• Journal: Journal of neurosurgery (J Neurosurg) Vol. 62 Issue 5 Pg. 767-71 (May 1985) ISSN: 0022-3085 [Print] United States
• PMID: 3921670 (Publication Type: Case Reports, Journal Article)

Chemical References

• Growth Hormone
• Growth Hormone-Releasing Hormone

Topics

• Acromegaly (etiology, pathology)
• Adult
• Female
• Growth Hormone (analysis)
• Growth Hormone-Releasing Hormone (analysis)
• Hemangiopericytoma (analysis, complications, pathology)
• Humans
• Lung Neoplasms (analysis, complications, pathology)
• Pituitary Neoplasms (analysis, complications, pathology)
• Sella Turcica