A review of epidemiological studies on artificial sweeteners and bladder cancer.

Abstract

Next to tobacco, saccharin may be the substance that has been most studied epidemiologically. Over 5000 patients with bladder cancer have participated in case-control studies; over 27,000 diabetics have been observed for 234,000 person-years. The summary relative risk from combining all case-control studies is less than 0.98, the standardized mortality ratio for bladder cancer in diabetics is only 70. Analysis of these studies leads to the conclusion that saccharin is not related to human bladder cancer.

• Authors: R W Morgan, O Wong
• Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association (Food Chem Toxicol) 1985 Apr-May Vol. 23 Issue 4-5 Pg. 529-33 ISSN: 0278-6915 [Print] England
• PMID: 3891558 (Publication Type: Journal Article, Review)

Chemical References

• Saccharin

Topics

• Humans
• Male
• Risk
• Saccharin (toxicity)
• Sex Factors
• Urinary Bladder Neoplasms (chemically induced)