Pepsinogen isozymes in Borrmann IV type gastric carcinoma.

Abstract

Immunoperoxidase staining for human group I and group II pepsinogens (PG I, PG II) was performed on stomachs including surgically removed 42 Borrmann IV type gastric carcinomas (B-IV), 6 duodenal ulcers and 6 autopsy cases of traffic accident. Besides, 8 surgical cases of B-IV were examined by polyacrylamide gel electrophoresis (PAGE). All 8 cases examined by PAGE showed positive finding for at least one pepsinogen isozyme. In male, 19/19 were positive while in female 21/23 were positive for PG I and/or PG II by the immuno-peroxidase method.

• Authors: K Nakamura, H Sue
• Journal: The Tohoku journal of experimental medicine (Tohoku J Exp Med) Vol. 145 Issue 1 Pg. 39-47 (Jan 1985) ISSN: 0040-8727 [Print] Japan
• PMID: 3885479 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Isoenzymes
• Pepsinogens
• Peptide Hydrolases

Topics

• Adult
• Aged
• Duodenal Ulcer (enzymology)
• Electrophoresis, Polyacrylamide Gel
• Female
• Humans
• Immunoenzyme Techniques
• Isoenzymes (analysis)
• Male
• Middle Aged
• Pepsinogens (analysis)
• Peptide Hydrolases (analysis)
• Stomach Neoplasms (enzymology)