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Fluoxetine in the treatment of obsessive compulsive disorder.

Abstract
In a 9-week open-label study, 7 outpatients with obsessive compulsive disorder were treated with fluoxetine, a selective inhibitor of neuronal reuptake of serotonin. A significant improvement was found in the symptomatology of patients as measured on the obsessive compulsive subscale of the Comprehensive Psychopathological Rating Scale (p less than 0.001) and the Clinical Global Impression of severity of illness (p less than 0.01). These findings support the hypothesis that serotoninergic antidepressants may be useful in the treatment of obsessive compulsive disorder.
AuthorsR Fontaine, G Chouinard
JournalProgress in neuro-psychopharmacology & biological psychiatry (Prog Neuropsychopharmacol Biol Psychiatry) Vol. 9 Issue 5-6 Pg. 605-8 ( 1985) ISSN: 0278-5846 [Print] England
PMID3878975 (Publication Type: Journal Article)
Chemical References
  • Propylamines
  • Fluoxetine
Topics
  • Adult
  • Female
  • Fluoxetine (adverse effects, therapeutic use)
  • Humans
  • Male
  • Middle Aged
  • Obsessive-Compulsive Disorder (drug therapy, psychology)
  • Propylamines (therapeutic use)
  • Psychiatric Status Rating Scales

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