Benoxaprofen--adverse reactions and monitoring in general practice.

Abstract

We report on the pattern of use of benoxaprofen (Opren) in a single group practice for a period which included the complete clinical life of the drug. One hundred and seventy-two patients of the 6495 practice patients had been prescribed benoxaprofen, but 55% had only a small exposure (less than 20 g). Recorded adverse reactions, of which none was serious, appeared in 25 patients. Most were taking benoxaprofen for osteoarthritis (53%) or non-specific musculoskeletal pain (39.9%). The issue of a prescription was not recorded in 19.6% of cases and 88% were on additional drugs. Greater precision in record-keeping is required to avoid problems similar to the experience with benoxaprofen.

• Authors: P G Newrick, D Bainton
• Journal: British journal of clinical pharmacology (Br J Clin Pharmacol) Vol. 23 Issue 2 Pg. 195-8 (Feb 1987) ISSN: 0306-5251 [Print] England
• PMID: 3828196 (Publication Type: Journal Article)

Chemical References

• Propionates
• benoxaprofen

Topics

• Adolescent
• Adult
• Age Factors
• Aged
• Child
• Drug Prescriptions
• Drug Utilization
• Female
• Humans
• Male
• Middle Aged
• Osteoarthritis (drug therapy)
• Propionates (adverse effects, therapeutic use)
• Risk
• United Kingdom