Comparison of self-hypnosis and propranolol in the treatment of juvenile classic migraine.

Abstract

In a prospective study we compared propranolol, placebo, and self-hypnosis in the treatment of juvenile classic migraine. Children aged 6 to 12 years with classic migraine who had no previous specific treatment were randomized into propranolol (at 3 mg/kg/d) or placebo groups for a 3-month period and then crossed over for 3 months. After this 6-month period, each child was taught self-hypnosis and used it for 3 months. Twenty-eight patients completed the entire study. The mean number of headaches per child for 3 months during the placebo period was 13.3 compared with 14.9 during the propranolol period and 5.8 during the self-hypnosis period. Statistical analysis showed a significant association between decrease in headache frequency and self-hypnosis training (P = .045). There was no significant change in subjective or objective measures of headache severity with either therapy.

• Authors: K Olness, J T MacDonald, D L Uden
• Journal: Pediatrics (Pediatrics) Vol. 79 Issue 4 Pg. 593-7 (Apr 1987) ISSN: 0031-4005 [Print] United States
• PMID: 3822681 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Propranolol

Topics

• Analysis of Variance
• Child
• Female
• Humans
• Hypnosis (methods)
• Male
• Migraine Disorders (drug therapy, therapy)
• Propranolol (therapeutic use)
• Prospective Studies
• Random Allocation