An unusual case of post-transfusion purpura: good transient response to high-dose immunoglobulin.

Abstract

A 62-year-old woman with an unusually protracted post-transfusion purpura failed to respond to three 3-litre plasma exchanges and prednisolone (50 mg/day) for 10 days but then had a good though transient response to two courses of high-dose immunoglobulin infusions with cessation of bleeding. The subsequent recurrent thrombocytopenia was mild and asymptomatic and only partially controlled by corticosteroids but finally resolved completely after 5 months.

• Authors: B H Chong, J Cade, J A Smith, J Tatoulis
• Journal: Vox sanguinis (Vox Sang) Vol. 51 Issue 3 Pg. 182-4 ( 1986) ISSN: 0042-9007 [Print] England
• PMID: 3811316 (Publication Type: Case Reports, Journal Article)

Chemical References

• Immunoglobulin G

Topics

• Dose-Response Relationship, Drug
• Female
• Humans
• Immunization, Passive
• Immunoglobulin G (administration & dosage, therapeutic use)
• Infusions, Intravenous
• Middle Aged
• Purpura, Thrombocytopenic (drug therapy, etiology, physiopathology)
• Transfusion Reaction