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Misclassification of environmental tobacco smoke exposure: its potential influence on studies of environmental tobacco smoke and lung cancer.

Abstract
The effects of selection, confounding, misclassification and bias must be eliminated from case-control studies of 'passive smoking' and lung cancer before a meaningful interpretation can be made. Misclassification includes the misclassification of the subject's non-smoking status, of the disease status or of the spouse's smoking habits. This paper shows that inflation of the amount smoked by the husbands of female lung cancer cases may have accounted for the apparent 'dose-response' relationships in 3 widely referenced case-control studies.
AuthorsS J Kilpatrick Jr
JournalToxicology letters (Toxicol Lett) Vol. 35 Issue 1 Pg. 163-8 (Jan 1987) ISSN: 0378-4274 [Print] Netherlands
PMID3810677 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Tobacco Smoke Pollution
Topics
  • Environmental Exposure
  • Humans
  • Interviews as Topic
  • Lung Neoplasms (etiology)
  • Marriage
  • Research
  • Statistics as Topic
  • Tobacco Smoke Pollution (adverse effects)

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