[Passive hemagglutination test in the serodiagnosis of syphilis].

Abstract

Passive haemagglutination test with pathogenic Treponema pallidum antigen in the serodiagnosis of syphilis, carried out on 752 sera (518 syphilitic patients and 234 subjects without evidence of syphilis) showed a greater general sensitivity as compared the cardiolipin tests and complement fixation test with Reiter protein antigen, and lower, to immunofluorescence (FTA--ABS). Its specificity is relatively lower than that of the cardiolopin and treponemal tests. Associated with the cardiolipin test it may be preferably used for the detection of syphilis, and moreover, passive haemagglutination may confirm the diagnosis in case of weak positive results with the FTA--ABS test. The latter is, however, essential for problem cases.

• Authors: M Georgescu, D Ionescu, S Dumitriu
• Journal: Revista de igiena, bacteriologie, virusologie, parazitologie, epidemiologie, pneumoftiziologie. Bacteriologia, virusologia, parazitologia, epidemiologia (Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Bacteriol Virusol Parazitol Epidemiol) 1979 Apr-Jun Vol. 24 Issue 2 Pg. 109-13 ISSN: 0376-4494 [Print] Romania
• Vernacular Title: Reacţia de hemaglutinare pasivă în serodiagnosticul sifilisului.
• PMID: 379958 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Antigens, Bacterial
• Cardiolipins

Topics

• Antigens, Bacterial
• Cardiolipins
• Complement Fixation Tests
• Fluorescent Antibody Technique
• Hemagglutination Tests
• Humans
• Syphilis Serodiagnosis (methods)
• Treponema pallidum