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[Various considerations in the treatment of amebic liver abscess].

Abstract
From 1974 to 1976 Acute Amoebic Hepatic Abscess treatment was viewed retrospectively with a random double blind prospective study administering metronidazol emetine, or a combination of both to three groups of 20 patients per group. The retrospective study of 1974 underlines the then predominant tendency toward a surgical management with a higher mortality (p less than 0.002). In 1976 medical treatment patients increased with a corresponding diminution of mortality (p less than 0.001). The prospective study showed no statistically significant response difference to the pharmacologic treatment variations. Here only 1.6% of patients underwent surgery and 1/3 of them received puncture drainage due to medical treatment failure. We conclude that non complicated acute amoebic liver abscess treatment should be medical, preferably with only one antiamoebic drug.
AuthorsA Esquivel López, G González Espínola, J R García Garduño, V Guarner Dalias
JournalRevista de gastroenterologia de Mexico (Rev Gastroenterol Mex) 1979 Apr-Jun Vol. 44 Issue 2 Pg. 51-6 ISSN: 0375-0906 [Print] Mexico
Vernacular TitleAlgunas consideraciones en el tratamiento del absceso hepático amibiano.
PMID379955 (Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article, Randomized Controlled Trial)
Chemical References
  • Placebos
  • Metronidazole
  • Emetine
Topics
  • Clinical Trials as Topic
  • Double-Blind Method
  • Drug Evaluation
  • Emetine (administration & dosage, therapeutic use)
  • Humans
  • Injections, Intramuscular
  • Liver Abscess, Amebic (drug therapy)
  • Metronidazole (administration & dosage, therapeutic use)
  • Placebos

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