Abstract |
Four adolescents with achalasia were treated with nifedipine. All the patients' symptoms improved dramatically. On manometric evaluation, following oral nifedipine, the lower esophageal sphincter pressure decreased approximately 50%. No change in esophageal peristaltic activity was noted. Side effects were minimal; two patients had mild headache initially. Nifedipine, which is commonly used in adult patients with achalasia, may be beneficial for short-term symptomatic relief in children until more definitive therapy can be performed.
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Authors | M Maksimak, D H Perlmutter, H S Winter |
Journal | Journal of pediatric gastroenterology and nutrition
(J Pediatr Gastroenterol Nutr)
1986 Nov-Dec
Vol. 5
Issue 6
Pg. 883-6
ISSN: 0277-2116 [Print] United States |
PMID | 3794905
(Publication Type: Case Reports, Journal Article, Research Support, U.S. Gov't, P.H.S.)
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Chemical References |
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Topics |
- Adolescent
- Child
- Deglutition Disorders
(etiology)
- Esophageal Achalasia
(complications, drug therapy, physiopathology)
- Esophagus
(physiopathology)
- Female
- Humans
- Male
- Manometry
- Nifedipine
(therapeutic use)
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