Cefuroxime axetil for treatment of uncomplicated gonorrhea.

Abstract	Oral cefuroxime axetil (1 g) plus probenecid cured 29 of 30 urethral and 6 of 6 rectal gonococcal infections in men; alone the drug cured 22 of 23 urethral and 4 of 6 rectal infections. No toxicity was observed. Cefuroxime axetil alone is effective for urethral gonorrhea in males; rectal gonorrhea probably requires additional probenecid.
Authors	A Gottlieb, J Mills
Journal	Antimicrobial agents and chemotherapy (Antimicrob Agents Chemother) Vol. 30 Issue 2 Pg. 333-4 (Aug 1986) ISSN: 0066-4804 [Print] United States
PMID	3767347 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)
Chemical References	Cephalosporins Amoxicillin Cefuroxime Probenecid cefuroxime axetil
Topics	Adolescent Adult Aged Amoxicillin (therapeutic use) Cefuroxime (analogs & derivatives, therapeutic use) Cephalosporins Drug Therapy, Combination Gonorrhea (drug therapy) Humans Male Middle Aged Probenecid (therapeutic use) Random Allocation Rectal Diseases (drug therapy) Urethritis (drug therapy)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!