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Single-dose therapy with trimethoprim-sulfametrole for chancroid in females.

Abstract
Women with genital ulcer disease who were culture-positive for Haemophilus ducreyi were treated with a single dose of the drug combination trimethoprim-sulfametrole; the dosage was 640 mg of trimethoprim and 3,200 mg of sulfametrole. All 27 women who were treated with this regimen and adequately followed were cured. Thus a single dose of trimethoprim-sulfametrole appears to be an effective treatment regimen for women with chancroid in Kenya.
AuthorsJ Dylewski, L J D'Costa, H Nsanze, A R Ronald
JournalSexually transmitted diseases (Sex Transm Dis) 1986 Jul-Sep Vol. 13 Issue 3 Pg. 166-8 ISSN: 0148-5717 [Print] United States
PMID3764627 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Drug Combinations
  • Sulfanilamides
  • Trimethoprim
  • sulfametrole
Topics
  • Adult
  • Chancroid (drug therapy)
  • Drug Combinations
  • Female
  • Genital Diseases, Female (drug therapy)
  • Humans
  • Sulfanilamides (administration & dosage, therapeutic use)
  • Trimethoprim (administration & dosage, therapeutic use)

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