Volitional movement is not preceded by cortical slow negativity in cerebellar dentate lesion in man.

Abstract

Slow negative potential preceding voluntary self-paced middle finger extension, as recorded from scalp electrodes by backward averaging technique, was absent in two patients with dyssynergia cerebellaris myoclonica (Ramsay Hunt syndrome); but present in two patients with cerebellar cortical degeneration. As the main pathological lesion in Ramsay Hunt syndrome is in the dentate nucleus and its efferent pathway, the present results are in conformity with the experimental finding that the premotor and motor cortices receive strong inputs from the cerebellar efferent system.

• Authors: H Shibasaki, G Barrett, R Neshige, I Hirata, H Tomoda
• Journal: Brain research (Brain Res) Vol. 368 Issue 2 Pg. 361-5 (Mar 19 1986) ISSN: 0006-8993 [Print] Netherlands
• PMID: 3697731 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Adolescent
• Adult
• Cerebellar Ataxia (physiopathology)
• Cerebellar Cortex (physiopathology)
• Electroencephalography
• Electromyography
• Female
• Humans
• Membrane Potentials
• Middle Aged
• Movement
• Myoclonic Cerebellar Dyssynergia (physiopathology)
• Nerve Degeneration
• Volition