HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Amyloidosis presented with whitening and loss of hair which improved after dimethylsulfoxide (DMSO) treatment.

Abstract
A 67-year-old male patient presented with rapid progression of whitening and loss of hair in past 2 months was consulted due to the suspicion of hypothyroidism. He had been told to have cardiomegaly for 3 years. Thyroid function was within normal limit. Prostate biopsy was performed because of prostatic hypertrophy and mild elevation of serum acid phosphatase. Amyloid accumulation was observed in the biopsy specimen. Subsequent skin biopsies revealed the same result. The scalp hair and beard grew and turned to black gradually several months after dimethyl sulfoxide (DMSO) treatment. These findings suggest that some of the manifestation of amyloidosis may respond to DMSO treatment.
AuthorsS D Hsieh, R Yamamoto, K Saito, Y Iwamoto, T Kuzuya, S Ohba, S Kobori, K Saito
JournalJapanese journal of medicine (Jpn J Med) Vol. 26 Issue 3 Pg. 393-5 (Aug 1987) ISSN: 0021-5120 [Print] Japan
PMID3694923 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Dimethyl Sulfoxide
Topics
  • Amyloidosis (complications, drug therapy, pathology)
  • Biopsy
  • Dimethyl Sulfoxide (administration & dosage, therapeutic use)
  • Hair Diseases (drug therapy, etiology)
  • Humans
  • Male
  • Middle Aged
  • Skin (pathology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: