HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

A comparative study of peritoneal fluid concentrations of oestradiol-17 beta, progesterone, and testosterone in controls and in patients with endometriosis.

Abstract
To ascertain whether a cyclical variation exists in the steroid hormone concentration of the peritoneal fluid between controls and patients with endometriosis, we set out to measure the concentration of oestradiol--17 beta (E2), progesterone (P4), and testosterone (T) by specific radioimmunoassay in the peritoneal fluid of these 2 groups. Forty six patients (mean age, 30.1 +/- 6 years) with pelvic endometriosis and 32 control patients (mean age, 32.2 + 3.8 years) without endometriosis were studied. The significance of differences between groups was determined by the Mann-Whitney mu test. In the control group a significant rise in peritoneal fluid E2 (P = 0.017) and P4 (P = 0.048) levels was observed in the luteal phase compared to the follicular phase, but no such difference was noted in women with endometriosis. It is suggested that peritoneal fluid steroid hormone assays are not helpful in the evaluation of ovarian function in endometriosis.
AuthorsP C Chew, A Loganath, R Gunasegaram, K L Peh, S R Kottegoda, S S Ratnam
JournalAnnals of the Academy of Medicine, Singapore (Ann Acad Med Singap) Vol. 16 Issue 2 Pg. 344-6 (Apr 1987) ISSN: 0304-4602 [Print] Singapore
PMID3688812 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Gonadal Steroid Hormones
  • Testosterone
  • Progesterone
  • Estradiol
Topics
  • Adult
  • Ascitic Fluid (analysis)
  • Endometriosis (metabolism)
  • Estradiol (analysis)
  • Female
  • Gonadal Steroid Hormones (analysis)
  • Humans
  • Ovary (metabolism)
  • Progesterone (analysis)
  • Testosterone (analysis)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: