cis-Diaminechloroplatinum in the treatment of advanced primary squamous cell carcinoma of the vaginal wall: a case report.

Abstract

A 34-year-old patient with advanced primary squamocellular vaginal carcinoma was treated with external radiation (4000 cGy to the pelvis) and a line source Cesium application delivering 4000 cGy to the vaginal wall. During this treatment the patient developed a lesion on her back that proved to be a metastasis of a squamocellular cancer. The patient was started on six courses of cisplatin as a single agent. After the fourth course a complete remission was reached lasting for 4 months. By that time the metastasis recurred and was surgically excised. Sixteen months after diagnosis and 9 months after chemotherapeutic treatment there is no evidence of disease.

• Authors: C A Holleboom, H C Kock, A M Nijs, W H Leers
• Journal: Gynecologic oncology (Gynecol Oncol) Vol. 27 Issue 1 Pg. 110-5 (May 1987) ISSN: 0090-8258 [Print] United States
• PMID: 3570044 (Publication Type: Case Reports, Journal Article)

Chemical References

• Cisplatin

Topics

• Adult
• Back
• Carcinoma, Squamous Cell (drug therapy, radiotherapy)
• Cisplatin (therapeutic use)
• Female
• Humans
• Neoplasm Metastasis
• Neoplasm Recurrence, Local
• Skin Neoplasms (drug therapy, pathology, secondary, surgery)
• Vaginal Neoplasms (drug therapy, radiotherapy)