Trial of nifedipine for prevention of oesophageal spasm.

Abstract

We have used a placebo controlled trial to investigate the effect of long-term administration of nifedipine in the prevention of symptomatic episodes of oesophageal spasm. Diary card scoring was used to assess symptoms in 8 patients with oesophageal spasm who were each given nifedipine and placebo for at least 6 weeks. No significant differences in symptoms between the nifedipine and placebo treatment periods were seen.

• Authors: H A Davies, M J Lewis, J Rhodes, A H Henderson
• Journal: Digestion (Digestion) Vol. 36 Issue 2 Pg. 81-3 ( 1987) ISSN: 0012-2823 [Print] Switzerland
• PMID: 3569678 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)

Chemical References

• Nifedipine

Topics

• Adult
• Double-Blind Method
• Drug Evaluation
• Esophageal Diseases (prevention & control)
• Female
• Humans
• Male
• Middle Aged
• Nifedipine (therapeutic use)
• Spasm (prevention & control)