Hypersensitivity reaction following chloramphenicol administration in a patient with typhoid fever.

Abstract	Hypersensitivity reactions due to chloramphenicol are rarely reported in the literature. We present a case report of a patient with typhoid fever who experienced a hypersensitivity reaction subsequent to the infusion of chloramphenicol sodium succinate. The patient had previously reacted similarly to ampicillin infusion. A brief review of reported cases of chloramphenicol hypersensitivity in the English-language literature, as well as possible alternative explanations in this case, are provided.
Authors	J B Perkins, R H Raasch
Journal	Drug intelligence & clinical pharmacy (Drug Intell Clin Pharm) Vol. 21 Issue 4 Pg. 343-5 (Apr 1987) ISSN: 0012-6578 [Print] United States
PMID	3569037 (Publication Type: Case Reports, Journal Article)
Chemical References	Chloramphenicol Ampicillin
Topics	Adult Ampicillin (adverse effects) Chloramphenicol (adverse effects) Drug Hypersensitivity (etiology) Dyspnea (chemically induced) Humans Male Typhoid Fever (drug therapy) Urticaria (chemically induced)

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