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Cisapride in non-ulcer dyspepsia. Results of a placebo-controlled trial.

Abstract
The effect of cisapride, 10 mg three times daily, was evaluated in a double-blind randomized study in 118 patients with non-ulcer dyspepsia. Peptic ulcer disease was excluded by endoscopy, gallstones by ultrasonography, and chronic pancreatitis by a series of non-invasive tests. Symptomatic improvement was evaluated by interview after 2 and 4 weeks; the patients also kept a diary. Cisapride caused significant improvement compared with placebo with regard to frequency and severity of symptoms and may therefore be useful in the therapy of non-ulcer dyspepsia.
AuthorsW Rösch
JournalScandinavian journal of gastroenterology (Scand J Gastroenterol) Vol. 22 Issue 2 Pg. 161-4 (Mar 1987) ISSN: 0036-5521 [Print] England
PMID3554491 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
Chemical References
  • Piperidines
  • Cisapride
Topics
  • Cisapride
  • Clinical Trials as Topic
  • Double-Blind Method
  • Dyspepsia (diagnosis, drug therapy)
  • Humans
  • Peptic Ulcer (diagnosis)
  • Piperidines (therapeutic use)
  • Random Allocation

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