Systemic administration of antibiotics in the management of venous ulcers. A randomized clinical trial.

Abstract	Forty-seven patients with chronic venous leg ulcers were included in a randomized clinical trial to evaluate the efficacy of systemically administered antibiotics in healing with condition. One group was treated by means of elastic support bandages only, whereas the other one received the same local treatment plus systemic antibiotics. No statistically relevant difference was noted between the two groups in healing rates of ulcers or in changes of the microbiologic flora. The results of our study do not support the routine administration of systemic antibiotics in the management of chronic venous leg ulcers.
Authors	A Alinovi, P Bassissi, M Pini
Journal	Journal of the American Academy of Dermatology (J Am Acad Dermatol) Vol. 15 Issue 2 Pt 1 Pg. 186-91 (Aug 1986) ISSN: 0190-9622 [Print] United States
PMID	3528240 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
Chemical References	Anti-Bacterial Agents
Topics	Aged Anti-Bacterial Agents (administration & dosage, therapeutic use) Bacteria (isolation & purification) Clinical Trials as Topic Female Humans Male Middle Aged Occlusive Dressings Random Allocation Varicose Ulcer (drug therapy, microbiology)

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