Abstract |
The effectiveness of oral ketotifen was compared with that of placebo in 26 patients with food allergy in a randomized, double-blind parallel study. Patients were selected on the basis of food allergy as established by history, clinical improvement after an exclusion diet, and reappearance of the symptoms after a challenge with the food. Thirteen patients were given ketotifen and 13, placebo. Ketotifen or placebo were administered twice daily for 1 month after the first oral provocation test and the last dose was given 12 hours before the second oral provocation test. Ketotifen protected patients (7/13) significantly more than placebo (2/13; P less than .05). The results of this study suggest that ketotifen may be useful for some patients with food allergy.
|
Authors | A L Boner, C Richelli, I Antolini, C Vibelli, L Andri |
Journal | Annals of allergy
(Ann Allergy)
Vol. 57
Issue 1
Pg. 61-4
(Jul 1986)
ISSN: 0003-4738 [Print] United States |
PMID | 3524320
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
|
Chemical References |
|
Topics |
- Adolescent
- Adult
- Child
- Child, Preschool
- Clinical Trials as Topic
- Double-Blind Method
- Female
- Food Hypersensitivity
(drug therapy)
- Humans
- Infant
- Ketotifen
(therapeutic use)
- Male
- Middle Aged
- Placebos
|