Adrenal phenylethanolamine-N-methyltransferase activity in the young rat: influence of thyroid hormones and insulin-induced hypoglycemia.

Abstract	The postnatal evolution of adrenal phenylethanolamine-N-methyltransferase (PNMT) activity is slightly accelerated by hypothyroidism and slowed by hyperthyroidism. In 14-day-old rats a single stimulation of the adrenals by insulin-induced hypoglycemia does not lead to any change in enzymatic activity. If the stimulation is repeated for 4 days, it leads to a net increase in adrenal PNMT activity in the control rats, while no increase occurs in hypo- or hyperthyroid animals.
Authors	D Gripois, M Valens
Journal	Biology of the neonate (Biol Neonate) Vol. 49 Issue 4 Pg. 219-23 ( 1986) ISSN: 0006-3126 [Print] Switzerland
PMID	3518820 (Publication Type: Journal Article)
Chemical References	Insulin Thyroid Hormones Phenylethanolamine N-Methyltransferase
Topics	Adrenal Glands (enzymology) Aging Animals Animals, Newborn (metabolism) Female Insulin (pharmacology) Male Phenylethanolamine N-Methyltransferase (antagonists & inhibitors, metabolism) Rats Thyroid Hormones (physiology)

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