Abstract |
An open field trial was conducted comparing desipramine and an active placebo in separate populations of chronic cocaine and phencyclidine (PCP) abusers, who discontinued their abuse. Subjects who received desipramine showed a decrease in depressive symptoms after a 20-40 day period regardless of whether they abused PCP or cocaine.
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Authors | A J Giannini, D A Malone, M C Giannini, W A Price, R H Loiselle |
Journal | Journal of clinical pharmacology
(J Clin Pharmacol)
Vol. 26
Issue 3
Pg. 211-4
(Mar 1986)
ISSN: 0091-2700 [Print] England |
PMID | 3514688
(Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, Journal Article)
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Chemical References |
- Placebos
- Cocaine
- Phencyclidine
- Desipramine
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Topics |
- Adult
- Clinical Trials as Topic
- Cocaine
- Depression
(drug therapy, etiology)
- Desipramine
(therapeutic use)
- Humans
- Male
- Phencyclidine
- Placebos
- Substance Withdrawal Syndrome
- Substance-Related Disorders
(complications)
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