Abstract |
The analgesic efficacy and tolerability of a morphine agonist-antagonist buprenorphine are evaluated. The drug is compared to pentazocin. For this purpose, the drugs were randomly administered to 42 patients suffering from pain caused by advanced cancer. Buprenorphine demonstrated a significantly higher analgesic effect than pentazocin and was better tolerated.
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Authors | D Dini, T Fassio, A Gottlieb, M Gini |
Journal | Minerva medica
(Minerva Med)
Vol. 77
Issue 3-4
Pg. 93-104
(Jan 28 1986)
ISSN: 0026-4806 [Print] Italy |
Vernacular Title | Studio controllato sull'effetto analgesico e sulla tollerabilità della buprenorfina, in pazienti affetti da neoplasia. |
PMID | 3511410
(Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Morphinans
- Buprenorphine
- Pentazocine
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Topics |
- Buprenorphine
(adverse effects, therapeutic use)
- Clinical Trials as Topic
- Drug Evaluation
- Female
- Humans
- Male
- Morphinans
(therapeutic use)
- Neoplasms
(drug therapy)
- Pain, Intractable
(drug therapy)
- Pentazocine
(adverse effects, therapeutic use)
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