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Tics in a patient with Parkinson's disease.

Abstract
A patient with Gilles de la Tourette syndrome later developed Parkinson's disease in middle age. This was accompanied by a marked reduction in the frequency of tics but levodopa toxicity exacerbated the tics. The dopamine hypothesis of tic disorders is supported by this observation.
AuthorsH Shale, S Fahn, R Mayeux
JournalMovement disorders : official journal of the Movement Disorder Society (Mov Disord) Vol. 1 Issue 1 Pg. 79-83 ( 1986) ISSN: 0885-3185 [Print] United States
PMID3504234 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Receptors, Dopamine
  • Levodopa
Topics
  • Humans
  • Levodopa (adverse effects)
  • Male
  • Middle Aged
  • Parkinson Disease (complications, drug therapy)
  • Receptors, Dopamine (physiology)
  • Tourette Syndrome (chemically induced, complications, physiopathology)

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