[Full remission of acute non-lymphatic leukemia lasting for 16 months following combination therapy with aclacinomycin A].

Abstract

After pretreatment with anthracyclines, a boy entered a second complete remission of an acute myeloid leukemia lasting already for 16 months following chemotherapy with Aclacinomycin A combined with Etoposide, Cytosine Arabinoside and Thioguanine. The newly developed Aclacinomycin A was well tolerated. Presumably there is no cross resistance between Aclacinomycin A and the anthracyclines, the latter being in use for the therapy of leukemias since some time.

• Authors: J D Beck
• Journal: Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde (Monatsschr Kinderheilkd) Vol. 134 Issue 8 Pg. 547-9 (Aug 1986) ISSN: 0026-9298 [Print] Germany
• Vernacular Title: Seit 16 Monaten anhaltende zweite Vollremission einer akuten nicht lymphatischen Leukämie nach Kombinationstherapie mit Aclacinomycin A.
• PMID: 3464845 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Antibiotics, Antineoplastic
• Naphthacenes
• Cytarabine
• Etoposide
• Aclarubicin
• Thioguanine

Topics

• Aclarubicin
• Antibiotics, Antineoplastic (administration & dosage)
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Child
• Cytarabine (administration & dosage)
• Drug Administration Schedule
• Etoposide (administration & dosage)
• Follow-Up Studies
• Humans
• Leukemia, Myeloid, Acute (drug therapy)
• Male
• Naphthacenes (administration & dosage)
• Thioguanine (administration & dosage)