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[Advantages and limitations of combined assays of 4 serum markers in various types of malignant neoplasms].

Abstract
CEA, TPA, GICA and Ferritin were assayed in 700 cancer patients (230 assays in 181 breast cancers, 75 in 57 lung cancers, 114 in 70 cervico-facial neoplasms, 131 in 95 uterovaginal tumours, 444 in 225 colorectal tumours, 106 in 72 gastric cancers). Groups were divided into stages and the results of all possible associations were assessed. Only the most significant are reported. Among combinations of 2 markers the combined assay of CEA and TPA offers the best response as diagnostic potential (expressed as percentage positivity) in all neoplasm groups as well as a good correlation with the evolution of the disease.
AuthorsE Lanza, C Coda, S Ramella, E Ciambellotti, G Moro, G L Cartia
JournalMinerva medica (Minerva Med) Vol. 77 Issue 34-35 Pg. 1521-5 (Sep 15 1986) ISSN: 0026-4806 [Print] Italy
Vernacular TitleVantaggi e limiti del dosaggio combinato di quattro markers sierici in diversi tipi di neoplasie maligne.
PMID3463886 (Publication Type: Comparative Study, English Abstract, Journal Article)
Chemical References
  • Antigens, Neoplasm
  • Antigens, Tumor-Associated, Carbohydrate
  • Carcinoembryonic Antigen
  • Peptides
  • Tissue Polypeptide Antigen
  • Ferritins
Topics
  • Antigens, Neoplasm (analysis)
  • Antigens, Tumor-Associated, Carbohydrate
  • Breast Neoplasms (diagnosis, immunology)
  • Carcinoembryonic Antigen (analysis)
  • Colonic Neoplasms (diagnosis, immunology)
  • Female
  • Ferritins (blood)
  • Genital Neoplasms, Female (diagnosis, immunology)
  • Head and Neck Neoplasms (diagnosis, immunology)
  • Humans
  • Lung Neoplasms (diagnosis, immunology)
  • Male
  • Peptides (analysis)
  • Radioimmunoassay
  • Rectal Neoplasms (diagnosis, immunology)
  • Stomach Neoplasms (diagnosis, immunology)
  • Tissue Polypeptide Antigen

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