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Topical hemostatic agents to reduce bleeding from cancellous bone surfaces: a comparison of Gelfoam paste and bone wax.

Abstract
This article reviews the history of topical bone hemostatic agents, listing advantages and disadvantages of the more commonly used agents. Gelfoam paste and bone wax were chosen to study the effects that bone hemostatic agents have on the occurrence and severity of postoperative edema and pain. The authors discovered 80% of the patients utilizing bone wax, and 91% of the patients receiving Gelfoam paste, had markedly decreased amounts of immediate postoperative edema. Furthermore, 90% of the patients treated with bone wax, and 75% of the patients treated with Gelfoam paste, reported less postoperative pain than anticipated with the surgical procedure performed.
AuthorsH Zirna, S E Keating, A F DeVincentis
JournalThe Journal of foot surgery (J Foot Surg) 1987 Nov-Dec Vol. 26 Issue 6 Pg. 496-500 ISSN: 0449-2544 [Print] United States
PMID3446704 (Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, Journal Article)
Chemical References
  • Drug Combinations
  • Hemostatics
  • Ointments
  • Palmitates
  • Palmitic Acids
  • Waxes
  • bone wax
Topics
  • Administration, Topical
  • Bone and Bones (surgery)
  • Drug Combinations (administration & dosage)
  • Gelatin Sponge, Absorbable (administration & dosage)
  • Hemostasis, Surgical (methods)
  • Hemostatics (administration & dosage)
  • Humans
  • Ointments
  • Palmitates (administration & dosage)
  • Palmitic Acids (administration & dosage)
  • Random Allocation
  • Waxes (administration & dosage)

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