Comparison of trichloroethylene and enflurane as adjuncts to nitrous oxide and relaxant anaesthesia.

Abstract

Forty women who underwent gynaecological surgery were randomly allocated to receive trichloroethylene, enflurane, or enflurane plus fentanyl as adjuncts to nitrous oxide/relaxant anaesthesia with controlled ventilation. No serious cardiac dysrhythmias were seen in any group. Each patient was observed postoperatively for 4 hours by a nurse blind to the technique used, and questioned at 24 hours by a similarly blinded anaesthetist. Recovery after trichloroethylene was not significantly prolonged although postoperative analgesia by visual analogue was better, opiate analgesia was required less frequently and there was less nausea and vomiting than in either of the enflurane groups. We argue for the continued use of trichloroethylene by this technique, because it costs one hundred times less than enflurane and because of the potential morbidity of the postoperative opiate dosage required after enflurane.

• Authors: A S Rice, F Reynolds
• Journal: Anaesthesia (Anaesthesia) Vol. 42 Issue 12 Pg. 1320-3 (Dec 1987) ISSN: 0003-2409 [Print] England
• PMID: 3434765 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Adjuvants, Anesthesia
• Trichloroethylene
• Enflurane
• Nitrous Oxide
• Alcuronium
• Fentanyl

Topics

• Adjuvants, Anesthesia
• Adult
• Alcuronium
• Anesthesia, Inhalation
• Enflurane (adverse effects)
• Female
• Fentanyl (adverse effects)
• Humans
• Intraoperative Complications (etiology)
• Nitrous Oxide
• Pain, Postoperative (prevention & control)
• Postoperative Complications (etiology)
• Trichloroethylene (adverse effects)