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The long term treatment with beta-carotene in erythropoietic protoporphyria: a controlled trial.

Abstract
The efficacy of oral beta-carotene for the prevention of photosensitivity symptoms in erythropoietic protoporphyria was studied in a controlled cross-over trial in which it was compared with a placebo. No significant difference was found between the 2 preparations. Patients' symptoms showed statistically significant association with sunlight hour records.
AuthorsM F Corbett, A Herxheimer, I A Magnus, C A Ramsay, A Kobza-Black
JournalThe British journal of dermatology (Br J Dermatol) Vol. 97 Issue 6 Pg. 655-62 (Dec 1977) ISSN: 0007-0963 [Print] England
PMID341955 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
Chemical References
  • Protoporphyrins
  • Carotenoids
Topics
  • Adult
  • Carotenoids (blood, therapeutic use)
  • Clinical Trials as Topic
  • Double-Blind Method
  • Erythrocytes (analysis)
  • Female
  • Humans
  • Male
  • Porphyrias (drug therapy)
  • Protoporphyrins (blood)
  • Sunlight

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