Single-dose cefotaxime intramuscularly cures gonococcal ophthalmia neonatorum.

Abstract

Nine neonates with culture proved gonococcal ophthalmia neonatorum were treated with a single intramuscular injection of 100 mg/kg of cefotaxime without topical antibiotic therapy. Five of the nine strains were penicillinase-producing Neisseria gonorrhoeae. All nine cases were clinically and microbiologically cured, and no side effects were observed.

• Authors: P Lepage, J Bogaerts, P Kestelyn, A Meheus
• Journal: The British journal of ophthalmology (Br J Ophthalmol) Vol. 72 Issue 7 Pg. 518-20 (Jul 1988) ISSN: 0007-1161 [Print] England
• PMID: 3415944 (Publication Type: Journal Article)

Chemical References

• Cefotaxime

Topics

• Cefotaxime (administration & dosage, therapeutic use)
• Female
• Humans
• Infant
• Infant, Newborn
• Injections, Intramuscular
• Male
• Ophthalmia Neonatorum (drug therapy)