Activity of febantel on natural infections of gastrointestinal helminths in lambs in a controlled test.

Abstract

The efficacy of febantel paste formulation (6 and 12 mg/kg) against natural infections of gastrointestinal helminths in lambs (n = 33) in Kentucky was evaluated in a controlled test. For the test, 23 lambs were treated orally (17 at 6 mg/kg and 6 at 12 mg/kg) and 10 lambs were not treated. Removals at both dosages in treated lambs were 95% to 100% for species of immature and mature Haemonchus, Trichostrongylus, and Cooperia; and mature Ostertagia females, Nematodirus, and Strongyloides. For immature Nematodirus, removals were 92% and 77% at the dosages of 6 and 12 mg/kg, respectively. Only a few specimens (av less than 100) of some other species or stages were found in the nontreated group and removal of them (at both dosages) were 94% to 100% for Ostertagia (immature and males), Strongyloides (immature), Oesophagostomum (immature), and Moniezia (mature); and 61% (at 6 mg/kg) and 100% (at 12 mg/kg) for Capillaria (mature), 0% for Trichuris (mature, at both dosages), and 67% (at 6 mg/kg) and 100% (at 12 mg/kg) for Oesophagostomum (mature).

• Authors: E T Lyons, J H Drudge, S C Tolliver
• Journal: American journal of veterinary research (Am J Vet Res) Vol. 49 Issue 6 Pg. 901-2 (Jun 1988) ISSN: 0002-9645 [Print] United States
• PMID: 3400926 (Publication Type: Journal Article)

Chemical References

• Anthelmintics
• Guanidines
• Ointments
• febantel

Topics

• Administration, Oral
• Animals
• Anthelmintics (administration & dosage, therapeutic use)
• Guanidines (administration & dosage, therapeutic use)
• Helminthiasis (drug therapy)
• Helminthiasis, Animal
• Intestinal Diseases, Parasitic (drug therapy, veterinary)
• Ointments
• Sheep
• Sheep Diseases (drug therapy)