Cyclic thymineless death significantly increases frequency of R-plasmid elimination.

Abstract

Thymine starvation of Escherichia coli strain C600 thy (R46) eliminated the R plasmid at a frequency of 17%. This was increased fourfold, to 68%, after the same culture was subjected to an additional three cycles of growth followed by thymineless death.

• Authors: M J Tribe, R J Pinney
• Journal: Antimicrobial agents and chemotherapy (Antimicrob Agents Chemother) Vol. 12 Issue 4 Pg. 555-6 (Oct 1977) ISSN: 0066-4804 [Print] United States
• PMID: 335962 (Publication Type: Journal Article)

Chemical References

• Thymine

Topics

• Escherichia coli (physiology)
• R Factors
• Thymine (physiology)
• Time Factors